代表性成果

1. Cheng-Yu Li, Bei Zheng, Jiang-Tao Li, Jia-ling Gao, Yu-Heng Liu, Dai-Wen Pang, Hong-Wu Tang*. Holographic Optical Tweezers and Boosting Upconversion Luminescent Resonance Energy Transfer Combined Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas12a Biosensors. ACS Nano, 2021, 15: 8142−8154.

2. Li Xia, Li-Juan Zhang, Hong-Wu Tang*, and Dai-Wen Pang. Revealing Microtubule-Dependent Slow-Directed Motility by SingleParticle Tracking. Analytical Chemistry, 2021, 93(12): 5211–5217

3. Bei Zheng, Ya-Feng Kang, Ting Zhang, Cheng-Yu Li, Sha Huang, Zhi-Ling Zhang, Qiong-Shui Wu, Chu-Bo Qi, Dai-Wen Pang, and Hong-Wu Tang*. Breaking Through Flow Bead Assay: Combination of Near-Infrared Optical Tweezers. Stabilizing and Upconversion Luminescence Encoding. Analytical Chemistry, 2020, 92(7): 5258-5266.

4. Ya-Feng Kang, Bei Zheng, Chengyu Li, Zhi-Ling Zhang, Hong-Wu Tang*, Qiongshui Wu, Dai-Wen Pang. Real-time Monitoring of Temperature Variations around a Gold Nanobipyramid Targeted Cancer Cell under Photothermal Heating by Actively Manipulating an Optically Trapped Luminescent Upconversion Microparticle. Analytical Chemistry, 2020, 92(1): 1292−1300.

5. Chengyu Li, Bei Zheng, Ya-Feng Kang, Hong-Wu Tang*, Dai-Wen Pang. Integrating 808 nm-Light-Excited Upconversion Luminescence Powering with DNA Tetrahedron Protection: An Exceptionally Precise and Stable Nanomachine for Intracelluar MicroRNAs Tracing. ACS Sensors, 2020, 5(1): 199−207.

6. Mingqiu Zheng, Yafeng Kang, Da Liu, Chengyu Li, Bei Zheng, Hongwu Tang*. Detection of ATP from "Fluorescence" to "Enhanced Fluorescence" Based on Metal- Enhanced Fluorescence Triggered by Aptamer Nanoswitch. Sensors and Actuators: B. Chemical. 2020, 319: 128263.

7. Cheng-Yu Li, Ya-Feng Kang, Chu-Bo Qi, Bei Zheng, Chun-Miao Xu, Yi Lin, Dai-Wen Pang, Hong-Wu Tang*. Incorporating luminescence-concentrating upconversion nanoparticles and DNA walkers into optical tweezers assisted imaging: a highly stable and ultrasensitive bead supported assay. Chemical Communications, 2020, 56: 6997-7000.

8. Qiong Li, Sihui Zhou, Ting Zhang, Bei Zheng, Hongwu Tang*. Bioinspired sensor chip for detection of miRNA-21 based on photonic crystals assisted cyclic enzymatic amplification method. Biosensors and Bioelectronics, 2020, 150: 111866.

9. Cheng-Yu Li, Ya-Feng Kang, Chu-Bo Qi, Bei Zheng, Ming-Qiu Zheng, Chong-Yang Song, Zhen-Zhong Guo, Yi Lin, Dai-Wen Pang, Hong-Wu Tang*. Breaking Through Bead-Supported Assay: Integration of Optical Tweezers Assisted Fluorescence Imaging and Luminescence Confined Upconversion Nanoparticles Triggered Luminescent Resonance Energy Transfer (LRET). Analytical Chemistry, 2019, 91(12): 7950-7957.

10. Ya-Feng Kang, Bei Zheng, Chong-Yang Song, Cheng-Yu Li, Zhi-Liang Chen, Qiong-Shui Wu, Yi Yang, Dai-Wen Pang, and Hong-Wu Tang*. Evaluation of Luminescence Properties of Single Hydrophilic Upconversion Nanoparticles by Optical Trapping. The Journal of Physical Chemistry C, 2019, 123 (15): 10107–10113.

11. Di Cao, Cheng-Yu Li, Chu-Bo Qi, Hong-Lei Chen, Dai-Wen Pang, and Hong-Wu Tang*. Multiple Optical Trapping Assisted Bead-Array Based Fluorescence Assay of Free and Total Prostate-specific Antigen in Serum. Sensors and Actuators B- Chemical, 2018, 269: 143–150.

12. Cheng-Yu Li, Di Cao, Chu-Bo Qi, Ya-Feng Kang, Chong-Yang Song, Dang-Dang Xu, Bei Zheng, Dai-Wen Pang, Hong-Wu Tang*.Combining Holographic Optical Tweezers with Upconversion Luminescence Encoding: Imaging-Based Stable Suspension Array for Sensitive Responding of Dual Cancer Biomarkers. Analytical Chemistry, 2018, 90(4): 2639-2647.

13. Dang-Dang Xu, Cui Liu, Cheng-Yu Li, Chong-Yang Song, Ya-Feng Kang, Chu-Bo Qi, Yi Lin, Dai-Wen Pang, Hong-Wu Tang*. Dual Amplification Fluorescence Assay for Alpha Fetal Protein Utilizing Immuno-Hybridization Chain Reaction and Metal-Enhanced Fluorescence of Carbon Nanodots. ACS Applied Materials and Interfaces, 2017, 9: 37606−37614.

14. Cheng-Yu Li, Di Cao, Chong-Yang Song, Chun-Miao Xu, Xu-Yan Ma, Zhi-Ling Zhang, Dai-Wen Pang, Hong-Wu Tang*. Integrating Optical Tweezers with Up-converting Luminescence: A Non-amplification Analytical Platform for Quantitative Detection of MicroRNA-21 Sequences. Chemical Communications, 2017, 53: 4092–4095.

15. Cheng-Yu Li, Di Cao , Chu-Bo Qi, Hong-Lei Chen, Ya-Tao Wan, Yi Lin, Zhi-Ling Zhang, Dai-Wen Pang, Hong-Wu Tang*. One-step Separation-free Detection of Carcinoembryonic Antigen in Whole Serum: Combination of Two-Photon Excitation Fluorescence and Optical Trapping. Biosensors and Bioelectronics, 2017, 90:146–152.

16. Yun-Liang Deng, Dang-Dang Xu, Dai-Wen Pang and Hong-Wu Tang*. Target-triggered Signal Turn-On Detection of Prostate Specific Antigen Based on Metal-Enhanced Fluorescence of Ag@SiO₂@SiO₂-RuBpy Composite Nanoparticles. Nanotechnology, 2017, 28: 065501.

17. Dang-Dang Xu,Yun-Liang Deng, Cheng-Yu Li, Yi Lin, and Hong-Wu Tang*. Metal-Enhanced Fluorescent Dye-doped Silica Nanoparticles and Magnetic Separation: A Sensitive Platform for One-Step Fluorescence Detection of Prostate Specific Antigen. Biosensors and Bioelectronics, 2017, 87, 881–887.

18. Cheng-Yu Li, Di Cao, Ya-Feng kang, Yi Lin, Ran Cui, Dai-Wen Pang, Hong-Wu Tang*. Fluorescence Detection of H5N1 Virus Gene Sequences Based on Optical Tweezers with Two-Photon Excitation Using a Single Near Infrared Nanosecond Pulse Laser.Analytical Chemistry, 2016, 88: 4432−4439.

19. Yu-Dan Ye, Li Xia, Dang-Dang Xu, Xiao-Jing Xing, Dai-Wen Pang, Hong-Wu Tang*. DNA-stabilized silver nanoclusters and carbon nanoparticles oxide: A sensitive platform for label-free fluorescence turn-on detection of HIV-DNA sequences. Biosensors and Bioelectronics, 2016, 85: 837– 843.

20. Di Cao, Cheng-Yu Li, Ya-Feng Kang, Yi Lin, Ran Cui, Dai-Wen Pang, Hong-Wu Tang*. Dual-component gene detection for H7N9 virus– The combination of optical trapping and bead-based fluorescence assay. Biosensors and Bioelectronics, 2016, 86: 1031–1037.

21. Xiao-Jing Xing, Wan-Lu Xiao, Xue-Guo Liu, Ying Zhou, Dai-Wen Pang, Hong-Wu Tang*, A fluorescent aptasensor using double-stranded DNA/graphene oxide as the indicator probe. Biosensors and Bioelectronics, 2016, 78: 431–437.

22. Ze-Zhong Chen, Li Cai, Min-Yan Chen, Yi Lin, Dai-Wen Pang, Hong-Wu Tang*. Indirect immunofluorescence detection of E. coli O157:H7 with fluorescent silica nanoparticles. Biosensors and Bioelectronics, 2015, 66: 95-102.

23. Xiao-Jing Xing, Ying Zhou, Dai-Wen Pang, Hong-Wu Tang*. Graphene Oxide and Metal-Mediated Base Pairs Based "Molecular Beacon" Integrating with Exonuclease І for Fluorescence Turn-on Detection of Biothiols. Small, 2014, 10(16): 3412–3420.

24. Zhi-Gang Wang, Shu-Lin Liu, Zhi-Ling Zhang, Zhi-Quan Tian, Hong-Wu Tang, Dai-Wen Pang*. Exploring Sialic Acid Receptors-Related Infection Behavior of Avian Influenza Virus in Human Bronchial Epithelial Cells by Single-Particle Tracking. Small, 2014, 10(13): 2712–2720.

25. Li Cai, Ze-Zhong Chen, Min-Yan Chen, Hong-Wu Tang*, Dai-Wen Pang. MUC-1 aptamer-conjugated dye-doped silica nanoparticles for MCF-7 cells detection. Biomaterials, 2013, 34: 371-381.

26. Yue He, Ling-Hong Xiong, Xiao-Jing Xing, Hong-Wu Tang*, Dai-Wen Pang. An ultra-high sensitive platform for fluorescence detection of micrococcal nuclease based on graphene oxide. Biosensors and Bioelectronics, 2013, 42: 467-473.

27. Xiao-Jing Xing, Xue-Guo Liu, Yue He, Yi Lin, Cui-Ling Zhang, Hong-Wu Tang*, Dai-Wen Pang. Amplified Fluorescent Sensing of DNA Using Graphene Oxide and a Conjugated Cationic Polymer. Biomacromolecules, 2013, 14(1): 117–123.

28. Yue He, Xiaojing Xing, Hongwu Tang*, Daiwen Pang.Graphene oxide based fluorescent biosensor for protein detection via terminal protection of small molecule-linked DNA. Small, 2013, 9(12): 2097–2101.

29. Yue He, Yi Lin, Hong-Wu Tang*, Dai-Wen Pang. A graphene oxide-based fluorescent aptasensor for the turn-on detection of epithelial tumor marker mucin 1. Nanoscale, 2012, 4: 2054–2059.

30. Xiao-Jing Xing, Xue-Guo Liu, Yue-He, Qing-Ying Luo,Hong-Wu Tang*, Dai-Wen Pang. Graphene Oxide Based Fluorescent Aptasensor for Adenosine Deaminase Detection Using Adenosine as the Substrate. Biosensors and Bioelectronics, 2012, 37: 61–67.

31. Li Cai, Ze-Zhong Chen, Xiao-Min Dong, Hong-Wu Tang*, Dai-Wen Pang. Silica nanoparticles based label-free aptamer hybridization for ATP detection using hoechst33258 as the signal reporter. Biosensors and Bioelectronics, 2011, 29: 46– 52.

32. Yue He, Zhi-Gang Wang, Hong-Wu Tang*, Dai-Wen Pang. Low background signal platform for the detection of ATP: When a molecular aptamer beacon meets graphene oxide. Biosensors and Bioelectronics, 2011, 29: 76– 81.

33. Hong-Wu Tang*, Xuebin B. Yang, Jennifer Kirkham, D. Alastair Smith. Probing Intrinsic and Extrinsic Components in Single Osteosarcoma Cells by Near-Infrared Surface-Enhanced Raman Scattering. Analytical Chemistry, 2007, 79(10): 3646–3653.