刘晓庆

博士 , 教授
研究方向: 分析化学
联系电话:
Email: xiaoqingliu@whu.edu.cn

教育与研究经历:

     2009年初从中国科学院长春应用化学研究所,电分析化学国家重点实验室获博士学位。2009至2015年先后在丹麦奥胡斯大学化学系、交叉学科纳米中心,以色列耶路撒冷希伯来大学化学研究所、纳米科学与技术中心工作。2015年加入武汉大学化学与分子科学学院,任教授、博士生导师。主要从事基于纳米技术的生物分析研究。曾获中科院刘永龄特等奖、中组部项目重点资助。

研究领域与兴趣:

    研究兴趣包括生物分析化学、DNA纳米技术、生物医学材料等。主要围绕核酸结构的组装与调控,开发先进材料与探针,用于传感检测、生物分析、精准诊疗研究。相关成果发表在Angew. Chem. Int. Ed., J. Am. Chem. Soc., Chem. Sci., Anal. Chem., Adv. Mater., Biomaterials, ACS Nano, Nano Lett., Acc. Chem. Res.等国际期刊八十余篇,授权专利6项。

招生招聘:

    在这里,有武大强力的学科支撑,有化院完善的科研条件,有我们积极向上、友爱互助的课题组氛围。欢迎化学、材料、医学或生物等学科背景的本科生、研究生以及博士后加入我们。http://xiaoqingliu.whu.edu.cn/

论文专利:

(1)     Min Pan, Qunying Jiang, Junlin Sun, Zhen Xu, Yizhuo Zhou, Li Zhang, Xiaoqing Liu*, Programming DNA Nanoassembly for Enhanced Photodynamic Therapy, Angew. Chem. Int. Ed., 2020, 59(5), 1897-1905.  https://doi.org/10.1002/anie.201915591 (Highlighted as Front Cover)

(2)     Wenxiao Wang, Yahua Liu, Tianhui Shi, Junlin Sun, Fengye Mo, Xiaoqing Liu*, Biosynthesized Quantum Dot for Facile and Ultrasensitive Electrochemical and Electrochemiluminescence Immunoassay, Anal. Chem.2020, 92(1), 1598-1604.  https://doi.org/10.1021/acs.analchem.9b04919

(3)     Qunying Jiang, Min Pan, Jialing Hu, Junlin Sun, Lei Fan, Zhiqiao Zou, Jianshuang Wei, Xiaoquan Yang, Xiaoqing Liu*, Regulation of Redox Balance Enhances Phototherapy Efficacy and Suppresses Tumor Metastasis Using a Biocompatible Nanoplatform, Chem. Sci., 2020, https://doi.org/10.1039/D0SC04983B (Highlighted as Outside Front Cover)

(4)     Junlin Sun, Min Pan, Feng Liu, Wenqian Yu, Wenxiao Wang, Fengye Mo, Shuyi Yu, Yizhuo Zhou, Xiaoqing Liu*, Immunostimulatory DNA Nanogel Enables Effective Lymphatic Drainage and High Vaccine Efficacy, ACS Materials Lett.2020, 1606–1614. https://doi.org/10.1021/acsmaterialslett.0c00445 (Highlighted as Supplementary Cover)

(5)     Feng Liu, Junlin Sun, Wenqian Yu, Qunying Jiang, Min Pan, Zhen Xu, Fengye Mo, Xiaoqing Liu*, Quantum Dot-Pulsed Dendritic Cell Vaccines Plus Macrophage Polarization for Amplified Cancer Immunotherapy, Biomaterials2020, 242, 119928. https://doi.org/10.1016/j.biomaterials.2020.119928

(6)     Wenqian Yu, Junlin Sun, Feng Liu, Shuyi Yu, Zhen Xu, Fuan Wang, Xiaoqing Liu*, Enhanced Immunostimulatory Activity of a Cytosine-Phosphate-Guanosine Immunomodulator by the Assembly of Polymer DNA Wires and Spheres, ACS Appl. Mater. Inter., 2020, 12(15), 17167-17176. https://doi.org/10.1021/acsami.9b21075

(7)     Huimin Wang, Dan Luo, Hong Wang, Fuan Wang, Xiaoqing Liu*, Construction of smart stimuli-responsive DNA nanostructures for biomedical applications, Chem. Eur. J., 2020, (Invited Review, ‡equal contribution)https://doi.org/10.1002/chem.202003145

(8)     Yahua Liu, Min Pan, Wenxiao Wang, Qunying Jiang, Fuan Wang, Dai-Wen Pang, Xiaoqing Liu*, Plasmonic and Photothermal Immunoassay via Enzyme-Triggered Crystal Growth on Gold Nanostars, Anal. Chem.2019, 91(3), 2086–2092. https://doi.org/10.1021/acs.analchem.8b04517

(9)     Jialing Hu, Fuan Wang, Feng Liu, Wentong Sun, Qunying Jiang, Yahua Liu, Yun Zhao, Xiaoqing Liu*, Effective Nanotherapeutic Approach for Metastatic Breast Cancer Treatment by Supplemental Oxygenation and Imaging-Guided Phototherapy, Nano Research2020, 13, 1111-1121. https://doi.org/10.1007/s12274-020-2753-5

(10) Wenqian Yu, Junlin Sun, Feng Liu, Shuyi Yu, Jialing Hu, Yun Zhao, Xiuyuan Wang, Xiaoqing Liu*, Treating Immunologically Cold Tumors by Precise Cancer Photoimmunotherapy with an Extendable Nanoplatform, ACS Appl. Mater. Inter., 2020, 12(36), 40002–40012. https://doi.org/10.1021/acsami.0c09469

(11) Li Zhang, Min Pan, Zhiqiao Zou, Lei Fan, Xiaoqing Liu*, Hybridization Chain Reaction-Mediated Luminescent Silver Nanocluster System for Amplified Detection of miRNA-21, Chin. J. Anal. Chem., 2020, 2020, 2020, 48(9): 1193-1201. DOI: 10.19756/j.issn.0253-3820.201144 (张丽, 潘敏, 邹芷乔, 樊蕾, 刘晓庆*, 杂交链式反应介导的发光银纳米簇系统用于miRNA-21的放大检测,分析化学, DOI: 10.19756/j.issn.0253-3820.201144)

(12) Lei Fan, Qunying Jiang, Min Pan, Wenxiao Wang, Li Zhang, Xiaoqing Liu*, Dual-Mode Sensing of Biomarkers by Mimic Enzyme-Natural Enzyme Cascade Signal Amplification, Acta Chim. Sinica 2020, 78, 419-426. http://www.ccspublishing.org.cn/article/doi/10.6023/A20030079 (樊蕾, 江群英, 潘敏, 王文晓, 张丽, 刘晓庆*, 基于模拟酶-天然酶级联反应的双模式传感平台用于生物标志物的超灵敏检测, 化学学报, DOI: 10.6023/A20030079)

(13) Jie Wei, Huimin Wang, Qiong Wu, Xue Gong, Kang Ma, Xiaoqing Liu, Fuan Wang*, A Smart, Autocatalytic, DNAzyme Biocircuit for inVivo, Amplified, MicroRNA Imaging, Angew. Chem. Int. Ed., 2020, 132, 6021-6027. https://doi.org/10.1002/ange.201911712

(14) Xue Gong, Ruomeng Li, Jing Wang, Jie Wei, Kang Ma, Xiaoqing Liu, Fuan Wang*, A smart theranostic nanocapsule for spatiotemporally programmable photo-genetherapy, Angew. Chem. Int. Ed., 2020, DOI: 10.1002/anie.202008413

(15) Huimin Wang†, Yuqi Chen†, Jinhua Shang, Hong Wang, Min Pan, Xiaoqing Liu, Xiang Zhou, Fuan Wang*, Multifunctional Hypoxia-Involved Gene Silencing Nanoplatform for Sensitizing Photochemotherapy. ACS Appl. Mater. Inter., 2020, 12(31), 34588–34598.

(16) Yangjie Zhou, Shanshan Yu, Jinhua Shang, Yingying Chen, Qing Wang, Xiaoqing Liu, Fuan Wang*, Construction of an Exonuclease III-Propelled Integrated DNAzyme Amplifier for Highly Efficient microRNA Detection and Intracellular Imaging with Ultralow Background. Anal. Chem., 2020, 92, 22, 15069–15078.

(17) Ping Dong, Yahua Liu, Yun Zhao, Wenxiao Wang, Min Pan, Yu Liu, Xiaoqing Liu*, Ratiometric Fluorescence Sensing of Copper Ion and Enzyme Activity by Nanoprobe-Mediated Autocatalytic Reaction and Catalytic Cascade Reaction, Sens. Actuators B Chem.2020, 310: 127873. https://doi.org/10.1016/j.snb.2020.127873

(18) Yun Zhao, Min Pan, Feng Liu, Yahua Liu, Ping Dong, Jie Feng, Tianhui Shi, Xiaoqing Liu*, Highly Selective and Sensitive Detection of Trinitrotoluene by Framework-Enhanced Fluorescence of Gold Nanoclusters, Anal. Chim. Acta.2020, 1106, 133-138. https://doi.org/10.1016/j.aca.2020.01.055

(19) Jie Feng#, Zhen Xu#, Dan Luo, Xiaoqing Liu*, Multiplexed Imaging with Coordination Nanoparticles for Cancer Diagnosis and Therapy, ACS Appl. Bio Mater.2020, 3(1), 713-720. https://doi.org/10.1021/acsabm.9b01038

(20) Jinhua Shang, Jie Wei, Qing Wang, Jing Wang, Yangjie Zhou, Shanshan Yu, Xiaoqing Liu, Fuan Wang*, Adaption of an Autonomously Cascade DNA Circuit for Amplified Detection and Intracellular Imaging of Polynucleotide Kinase with Ultralow Background, Biosens. Bioelectron., 2020, 152, 111994. DOI: 10.1016/j.bios.2019.111994

(21) Meijuan Liang, Minyi Zhang, Shanshan Yu, Qiong Wu, Kang Ma, Yingying Chen, Xiaoqing Liu, Chunsen Li*, Fuan Wang*, Silver-Laden Black Phosphorus Nanosheets for an Efficient In Vivo Antimicrobial Application, Small, 2020, 16(13), 1905938. DOI: 10.1002/smll.201905938

(22) Junlin Sun, Feng Liu, Wenqian Yu, Qunying Jiang, Jialing Hu, Yahua Liu, Fuan Wang, Xiaoqing Liu*, Highly Sensitive Glutathione Assay and Intracellular Imaging with Functionalized Semiconductor Quantum Dots, Nanoscale2019, 11(11), 5014–5020. https://doi.org/10.1039/C8NR09801H

(23) Yahua Liu, Ping Dong, Qunying Jiang, Fuan Wang, Dai-Wen Pang, Xiaoqing Liu*, Assembly-Enhanced Fluorescence from Metal Nanoclusters and Quantum Dots for Highly Sensitive Biosensing, Sens. Actuators B Chem. 2019, 279(15), 334–341. https://doi.org/10.1016/j.snb.2018.10.016

(24) Min Pan, Zhen Xu, Qunying Jiang, Jie Feng, Fuan Wang, Xiaoqing Liu*, Interfacial Engineering of Carbon Dots with Benzenediboronic Acid for Fluorescent Biosensing, Nanoscale Adv., 2019, 1(2), 765-771. https://doi.org/10.1039/C8NA00166A

(25) Jie Feng, Zhen Xu, Ping Dong, Wenqian Yu, Feng Liu, Qunying Jiang, Fuan Wang, Xiaoqing Liu*, Stimuli-Responsive Multifunctional Metal-Organic Framework Nanoparticles for Enhanced Chemo-Photothermal Therapy, J Mater. Chem. B, 2019, 7(6), 994–1004. https://doi.org/10.1039/C8TB02815J

(26) Huimin Wang, Yuqi Chen, Hong Wang, Xiaoqing Liu, Xiang Zhou, Fuan Wang*, DNAzyme-Loading MOFs for Self-Sufficient Gene Therapy, Angew. Chem. Int. Ed.2019, 58(22), 7380-7384. https://doi.org/10.1002/anie.201902714

(27) Jing Wang, Huimin Wang, Hong Wang, Shizhen He, Ruomeng Li, Zhao Deng, Xiaoqing Liu, Fuan Wang*, Nonviolent Self-Catabolic DNAzyme Nanosponges for Smart Anticancer Drug Delivery, ACS Nano2019, 13(5), 5852–5863. https://doi.org/10.1021/acsnano.9b01589

(28) Qiong Wu, Gang Chen, Keke Gong, Jing Wang, Xiaoxiao Ge, Xiaoqing Liu, Shaojun Guo*, FuanWang*, MnO2-Laden Black Phosphorus for MRI-Guided Synergistic PDT, PTT, and Chemotherapy, Matter2019, 1(2), 496–512. https://doi.org/10.1016/j.matt.2019.03.007

(29) Hong Wang, Huimin Wang, Qiong Wu, Meijuan Liang, Xiaoqing Liu, Fuan Wang*, DNAzyme-amplified DNA Circuit for Highly Accurate MicroRNA Detection and Intracellular Imaging, Chem. Sci., 2019, 10(41), 9597–9604.

(30) Xue Gong, Jie Wei, Jing Liu, Ruomeng Li, Xiaoqing Liu, Fuan Wang*, Programmable Intracellular DNA Biocomputing Circuits for Reliable Cell Recognitions, Chem. Sci., 2019, 10(10), 2989-2997.

(31) Kaiyue Tan, Yingying Chen, Kang Ma, Qing Wang, Xiaoqing Liu, Fuan Wang*, Spatiotemporally Tracking the Programmable Mitochondrial Membrane Potential Evolutions by a Robust Molecular Rotor, Small2019, 15(40), 1903266. https://doi.org/10.1002/smll.201903266

(32) Lei Yang, Qiong Wu, Yuqi Chen, Xiaoqing Liu, Fuan Wang*, Xiang Zhou, Amplified MicroRNA Detection and Intracellular Imaging Based on an Autonomous and Catalytic Assembly of DNAzyme, ACS Sens.2019, 4(1), 110-117. 

(33) Qiong Wu, Hong Wang, Keke Gong, Jinhua Shang, Xiaoqing Liu, Fuan Wang*, Construction of an Autonomous Nonlinear Hybridization Chain Reaction for Extracellular Vesicles-Associated microRNAs Discrimination, Anal. Chem.2019, 91(15), 10172–10179. 

(34) Lana Zou, Qiong Wu, Yangjie Zhou, Xue Gong, Xiaoqing Liu, Fuan Wang*, DNAzyme-Powered Cross-Catalytic Circuit for Amplified Intracellular Imaging, Chem. Commun.2019, 55(46), 6519–6522. 

(35) Jie Feng, Zhen Xu, Feng Liu, Yun Zhao, Wenqian Yu, Min Pan, Fuan Wang, Xiaoqing Liu*, Versatile Catalytic Deoxyribozyme Vehicles for Multimodal Imaging-Guided Efficient Gene Regulation and Photothermal Therapy, ACS Nano2018, 12 (12), 12888–12901. https://doi.org/10.1021/acsnano.8b08101

(36) Min Pan#, Meijuan Liang#, Junlin Sun, Xiaoqing Liu*, Fuan Wang*, Lighting Up Fluorescent Silver Clusters via Target-Catalyzed Hairpin Assembly for Amplified Biosensing, Langmuir2018, 34(49), 14851–14857.  https://doi.org/10.1021/acs.langmuir.8b01576

(37) Meijuan Liang, Min Pan, Jialing Hu, Fuan Wang, Xiaoqing Liu*, Electrochemical Biosensor for MicroRNA Detection Based on Cascade Hybridization Chain Reaction, ChemEletroChem, 2018, 5(10), 1380–1386.  https://doi.org/10.1002/celc.201800255  (VIP, Very Important Paper)

(38) Huimin Wang, Chunxiao Li, Xiaoqing Liu, Xiang Zhou, Fuan Wang*, Construction of an Enzyme-Free Concatenated DNA Circuit for Signal Amplification and Intracellular Imaging, Chem. Sci., 2018, 9(26), 5842–5849. https://doi.org/10.1039/C8SC01981A

(39) Jie Wei, Xue Gong, Qing Wang, Min Pan, Xiaoqing Liu, Jing Liu, Fan Xia, Fuan Wang*, Construction of an Autonomously Concatenated Hybridization Chain Reaction for Signal Amplification and Intracellular Imaging, Chem. Sci., 2018, 9(1), 52–61.

(40) Chunxiao Li, Huimin Wang, Jinhua Shang, Xiaoqing Liu, Bi-Feng Yuan, Fuan Wang*, Highly Sensitive Assay of Methyltransferase Activity Based on an Autonomous Concatenated DNA Circuit, ACS Sens., 2018, 3(11), 2359–2366. https://doi.org/10.1021/acssensors.8b00738

(41) Qiong Wu, Meijuan Liang, Simin Zhang, Xiaoqing Liu, Fuan Wang*, Development of Functional Black Phosphorus Nanosheets with Remarkable Catalytic and Antibacterial Performance, Nanoscale, 2018, 10, 10428–10435. https://doi.org/10.1039/C8NR01715H

(42) Qing Wang, Min Pan, Jie Wei, Xiaoqing Liu, Fuan Wang*, Evaluation of DNA Methyltransferase Activity and Inhibition via Isothermal Enzyme-Free Concatenated Hybridization Chain Reaction, ACS Sens., 2017, 2(7), 932–939. https://doi.org/10.1021/acssensors.7b00168

(43) Jing Wang, Min Pan, Jie Wei, Xiaoqing Liu, Fuan Wang*, A C-HCR Assembly of Branched DNA Nanostructures for Amplified Uracil-DNA Glycosylase Assays, Chem. Commun., 2017, 53(96), 12878–12881.

(44) Fuan Wang†, Xiaoqing Liu†, Itamar Willner*, DNA Switches: From Principles to Applications. Angew. Chem. Int. Ed. 2015, 54, 1098–1129. (†Equal Contribution)  https://doi.org/10.1002/anie.201404652

(45) Xiaoqing Liu†, Chun-Hua Lu†, Itamar Willner*, Switchable Reconfiguration of Nucleic Acid Nanostructures by Stimuli-Responsive DNA Machines. Acc. Chem. Res. 2014, 47, 1673–1680. (†Equal Contribution)  DOI: https://doi.org/10.1021/ar400316h

(46) Lianzhe Hu, Xiaoqing Liu, Alessandro Cecconello, Itamar Willner, Dual Switchable CRET-Induced Luminescence of CdSe/ZnS Quantum Dots (QDs) by the Hemin/G-Quadruplex-Bridged Aggregation and Deaggregation of Two-Sized QDs. Nano Lett. 2014, 14, 6030-6035. (†Equal Contribution) https://doi.org/10.1021/nl503299f

(47) Fuan Wang, Chun-Hua Lu, Xiaoqing Liu, Lina Freage, Itamar Willner*, Amplified and Multiplexed Detection of DNA Using the Dendritic Rolling Circle Amplified Synthesis of DNAzyme Reporter Units. Anal. Chem. 2014, 86, 1614–1621. DOI: 10.1021/ac4033033

(48) Chun-Hua Lu, Xiu-Juan Qi, Xiaoqing Liu, Simcha Shimron, Huang-Hao Yang, Itamar Willner*, Autonomous Control of Interfacial Electron Transfer and the Activation of DNA Machines by an Oscillatory pH System. Nano Lett. 2013, 13, 4920–4924, DOI: 10.1021/nl402873y

(49) Xiaoqing Liu, Fuan Wang, Ruth Aizen, Omer Yehezkeli, Itamar Willner*, Graphene Oxide/Nucleic Acid-Stabilized Silver Nanoclusters: Functional Hybrid Materials for Optical Aptamer Sensing and Multiplexed Analysis of Pathogenic DNAs. J. Am. Chem. Soc. 2013, 135, 11832–11839. https://doi.org/10.1021/ja403485r

(50) Fuan Wang, Xiaoqing Liu, Chun-Hua Lu, Itamar Willner*, Cysteine-Mediated Aggregation of Au Nanoparticles: The Development of a H2O2 Sensor and Oxidase-Based Biosensors. ACS Nano, 2013, 7, 7278–7286. DOI: 10.1021/nn402810x

(51) Gilad Pelossof, Ran Tel-Vered, Xiaoqing Liu, Itamar Willner*, Switchable Mechanical DNA “Arms” Operating on Nucleic Acid Scaffolds Associated with Electrodes or Semiconductor Quantum Dots. Nanoscale, 2013, 5, 8977–8981. DOI: 10.1039/C3NR02653A

(52) Xiaoqing Liu, Fuan Wang, Angelica Niazov-Elkan, Weiwei Guo, Itamar Willner*, Probing Biocatalytic Transformations with Luminescent DNA/Ag Nanoclusters. Nano Lett. 2013, 13, 309–314. https://doi.org/10.1021/nl304283c

(53) Xiaoqing Liu, Angelica Niazov-Elkan, Fuan Wang, Itamar Willner*, Switching Photonic and Electrochemical Functions of a DNAzyme by DNA Machines. Nano Lett. 2013, 13, 219–225.https://doi.org/10.1021/nl303894h

(54) Fuan Wang, Xiaoqing Liu, Itamar Willner*, Integration of Photoswitchable Proteins, Photosynthetic Reaction Centers and Semiconductor/Biomolecule Hybrids with Electrode Supports for Optobioelectronic Applications. Adv. Mater. 2013, 25, 349–377. DOI: 10.1002/adma.201201772

(55) Etery Sharon, Xiaoqing Liu, Ronit Freeman, Omer Yehezkeli, Itamar Willner*, Label-Free Analysis of Thrombin or Hg2+ Ions by Nucleic Acid-Functionalized Graphene Oxide Matrices Assembled on Field-Effect Transistors. Electroanalysis 2013, 25, 851–856. DOI:10.1002/elan.201200581

(56) Xiaoqing Liu, Ruth Aizen, Ronit Freeman, Omer Yehezkeli, Itamar Willner*, Multiplexed Aptasensors and Amplified DNA Sensors Using Functionalized Graphene Oxide: Application for Logic Gate Operations. ACS Nano 2012, 6, 3553–3563.https://doi.org/10.1021/nn300598q

(57) Xiaoqing Liu, Freeman Ronit, Itamar Willner*, Amplified Fluorescence Aptamer-Based Sensors Using Exonuclease III for the Regeneration of the Analyte. Chem. Eur. J. 2012, 18, 2207–2211.  https://doi.org/10.1002/chem.201103342

(58) Zhanxia Zhang, Etery Sharon, Ronit Freeman, Xiaoqing Liu, Itamar Willner*, Fluorescence Detection of DNA, Adenosine-5'-Triphosphate and Telomerase Activity by Zn(II)-Protoporphyrin IX/G-Quadruplex as Label. Anal. Chem. 2012, 84, 4789–4797. DOI: 10.1021/ac300348v

(59) Ronit Freeman†, Xiaoqing Liu†, Itamar Willner*, Chemiluminescent and Chemiluminescence Resonance Energy Transfer (CRET) Detection of DNA, Metal Ions, and Aptamer_Substrate Complexes Using Hemin/G-Quadruplexes and CdSe/ZnS Quantum Dots. J. Am. Chem. Soc. 2011, 133, 11597–11604. (†Equal Contribution) https://doi.org/10.1021/ja202639m

(60) Xiaoqing Liu, Ronit Freeman, Eyal Golub, Itamar Willner*, Chemiluminescence and Chemiluminescence Resonance Energy Transfer (CRET) Aptamer Sensors Using Catalytic Hemin/G-Quadruplexes. ACS Nano 2011, 5, 7648–7655.https://doi.org/10.1021/nn202799d

(61) Ronit Freeman, Xiaoqing Liu, Itamar Willner*, Amplified Multiplexed Analysis of DNA by the Exonuclease III-Catalyzed Regeneration of the Target DNA in the Presence of Functionalized Semiconductor Quantum Dots. Nano Lett. 2011, 11, 4456–4461. https://doi.org/10.1021/nl202761g

(62) Gilad Pelossof, Ran Tel-Vered, Xiaoqing Liu, Itamar Willner*, Amplified Surface Plasmon Resonance-Based DNA Biosensors, Aptasensors, and Hg2+ Sensors Using Hemin/G-Quadruplexes and Au Nanoparticles. Chem. Eur. J. 2011, 17, 8904–8912. DOI: 10.1002/chem.201100601

(63) Xiaoqing Liu, Fuan Wang, Yuling Wang, Shuyun Zhu, Guobao Xu*, Functionalized Single-Walled Carbon Nanohorns for Electrochemical Biosensing. Biosens. Bioelectron. 2010, 25, 2194-2199. DOI: 10.1016/j.bios.2010.02.027

(64) Xiaoqing Liu, Fuan Wang, Shuang Han, Lihong Shi, Guobao Xu*, Self-Assembly of gold Nanoparticles/Electroactive Polyelectrolyte Multilayer Films for Tunable Electrocatalysis. Electroanalysis 2010, 22, 963-969. DOI: 10.1002/elan.200900479

(65) Fuan Wang, Xiaoqing Liu, Gaiping Li, Dan Li, Shaojun Dong*, Selective Electrodissolution of Inorganic Ions/DNA Multilayer Film for Tunable DNA Release. J. Mater. Chem. 2009, 19, 286–291. DOI: 10.1039/B812940A

(66) Lihong Shi, Xiaoqing Liu, Wenxin Niu, Haijuan Li, Shuang Han, Jiuan Chen, Guobao Xu*, Hydrogen Peroxide Biosensor Based on Direct Electrochemistry of Soybean Peroxidase Immobilized on Single-Walled Carbon Nanohorn Modified Electrode. Biosens. Bioelectron. 2009, 24, 1159–1163. DOI: 10.1016/j.bios.2008.07.001

(67) Wenxin Niu, Shanliang Zheng, Dawei Wang, Xiaoqing Liu, Haijuan Li, Shuang Han, Jiuan Chen, Zhiyong Tang*, Guobao Xu*, Selective Synthesis of Single-Crystalline Rhombic Dodecahedral, Octahedral, and Cubic Gold Nanocrystals. J. Am. Chem. Soc. 2009, 131, 697–703. DOI: 10.1021/ja804115r

(68) Haijuan Li, Jiuan Chen, Shuang Han, Wenxin Niu, Xiaoqing Liu, Guobao Xu*, Electrochemiluminescence from Tris(2,2'-Bipyridyl)Ruthenium(II)-Graphene-Nafion Modified Electrode. Talanta 2009, 79, 165-170. DOI: 10.1016/j.talanta.2009.03.020

(69) Haijuan Li, Lihong Shi, Xiaoqing Liu, Wenxin Niu, Guobao Xu*, Determination of Isocyanates by Capillary Electrophoresis with Tris(2,2'-bipyridine)ruthenium(II) Electrochemiluminescence. Electrophoresis 2009, 30, 3926–39316. DOI: 10.1002/elps.200900281

(70) Xiaoqing Liu, Lihong Shi, Wenxin Niu, Haijuan Li, Guobao Xu*, Amperometric Glucose Biosensor Based on Single-Walled Carbon Nanohorns. Biosens. Bioelectron. 2008, 23, 1887–1890. DOI: 10.1016/j.bios.2008.02.016

(71) Xiaoqing Liu, Wenxin Niu, Haijuan Li, Shuang Han, Lihong Shi, Guobao Xu*, Glucose Biosensor Based on Gold Nanoparticle-Catalyzed Luminol Electrochemiluminescence on a Three-Dimensional Sol-Gel Network. Electrochem. Commun. 2008, 10, 1250–1253. DOI: 10.1016/j.elecom.2008.06.009

(72) Haijuan Li, Xiaoqing Liu, Wenxin Niu, Shuyun Zhu, Lishuang Fan, Lihong Shi, Guobao Xu*, Capillary Electrochromatography with Tris(2,2'-bipyridyl) Ruthenium(II) Electrochemiluminescent Detection. Electrophoresis 2008, 29, 4475–4481. DOI: 10.1002/elps.200800088

(73) Fuan Wang, Dan Li, Gaiping Li, Xiaoqing Liu, Shaojun Dong*, Electrodissolution of Inorganic ions/DNA Multilayer Film for Tunable DNA Release. Biomacromolecules 2008, 9, 2645–2652. DOI: 10.1021/bm800766t

(74) Fuan Wang, Jianlong Wang, Xiaoqing Liu, Shaojun Dong*, Nanoparticle-amplified Surface Plasmon Resonance Study of Protein Conformational Change at Interface. Talanta 2008, 77, 628–634. DOI: 10.1016/j.talanta.2008.06.042

(75) Shuyun Zhu, Lishuang Fan, Xiaoqing Liu, Lihong Shi, Haijuan Li, Shuang Han, Guobao Xu*. Determination of Concentrated Hydrogen Peroxide at Single-Walled Carbon Nanohorn Paste Electrode. Electrochem. Commun. 2008, 10, 695–698. DOI: 10.1016/j.elecom.2008.02.020

(76) Wenxin Niu, Zhi-Yuan Li, Lihong Shi, Xiaoqing Liu, Haijuan Li, Shuang Han, Jiuan Chen, Guobao Xu*, Seed-mediated Growth of Nearly Monodisperse Palladium Nanocubes with Controllable Sizes, Cryst. Growth. Des. 2008, 8, 4440-4444. DOI: 10.1021/cg8002433

(77) Xiaoqing Liu, Lihong Shi, Wenxin Niu, Haijuan Li, Guobao Xu*, Environmentally Friendly and Highly Sensitive Ruthenium(II) Tris(2,2'-bipyridyl) Electrochemiluminescent System Using 2-(dibutylamino)ethanol as Co-Reactant. Angew. Chem. Int. Ed. 2007, 46, 421–424. DOI: 10.1002/anie.200603491 (VIP, Very Important Paper)

(78) Xiaoqing Liu, Lihong Shi, Haijuan Li, Wenxin Niu, Guobao Xu*, Tris(2,2'-bipyridyl)ruthenium(II) Electrochemiluminescent Detection of Coreactants Containing Aromatic Diol Group by the Interaction Between Diol and Borate Anion. Electrochem. Commun. 2007, 9, 2666–2670. DOI: 10.1016/j.elecom.2007.08.017

(79) Jing Li, Minghua Huang, Xiaoqing Liu, Hui Wei, Yuanhong Xu, Guobao Xu, Erkang Wang*, Enhanced Electrochemiluminescence Sensor from Tris(2,2'-Bipyridyl)Ruthenium(II) Incorporated into MCM-41 and an Ionic Liquid-Based Carbon Paste Electrode. Analyst 2007, 132, 687–691. DOI: 10.1039/B701842H

(80) Shuang Han, Junfeng Zhai, Lihong Shi, Xiaoqing Liu, Haijuan Li, Guobao Xu*, Rotating Minidisk-Disk Electrodes, Electrochem. Commun. 2007, 9, 1434-1438. DOI: 10.1016/j.elecom.2007.01.052

(81) Lianzhe Hu, Haijuan Li, Shuyun Zhu, Lishuang Fan, Lihong Shi, Xiaoqing Liu, Guobao Xu*, Cathodic Electrochemiluminescence in Aqueous Solutions at Bismuth Electrodes. Chem. Commun. 2007, 40, 4146-4148. DOI: 10.1039/B709612G

(82) Lihong Shi, Xiaoqing Liu, Haijuan Li, Wenxin Niu, Guobao Xu*, Application of Ceramic Carbon Materials for Solid-Phase Extraction of Organic Compounds. Anal. Chem. 2006, 78, 1345–1348. DOI: 10.1021/ac051894e

(83) Lihong Shi, Xiaoqing Liu, Haijuan Li, Guobao Xu*, Electrochemiluminescent Detection Based on Solid-Phase Extraction at Tris(2,2'-Bipyridyl)Ruthenium(II)-Modified Ceramic Carbon Electrode. Anal. Chem. 2006, 78, 7330–7334. DOI: 10.1021/ac060767v

(84) Lihong Shi, Xiaoqing Liu, Haijuan Li, Guobao Xu*, Determination of Total Calcium in Plasma by Flow Injection Analysis with Tris(2,2׳-Bipyridyl)Ruthenium(II) Electrochemiluminescent Detection. Electroanalysis 2006, 18, 1584–1589. DOI: 10.1002/elan.200603555

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