承担项目与课题
1. 主持国家杰出青年科学基金: 催化不对称1,3-偶极环加成 (21525207, 2016.1-2020.12)
2. 主持国家自然科学基金: Azomethine Ylide参与的催化不对称[6+3]-环加成反应研究 (21372180, 2014.1-2017.12)
3. 主持国家自然科学基金: 新型手性配体TF-BiphamPhos设计合成及其在催化不对称反应中的应用研究 (21172176, 2012.1-2015.12)
4. 主持国家自然科学基金: 多氢键给体协同活化策略在手性氨基－硫脲类双官能团有机小分子催化反应中的应用研究 (20972117, 2010.1-2012.12)
5. 主持国家自然科学基金: 基于中心手性诱导的新型轴手性双膦配体的设计、合成及其应用研究 (20702039, 2008.1-2010.12)
6. 主持国家自然科学基金: 新型手性二胺和其衍生物的设计合成与在不对称催化反应中应用研究 (20642005, 2007.1-2007.12)
7. 主持教育部新世纪优秀人才支持计划 (NCET-10-0649, 2011.1-2013.12)
8. 主持湖北省自然科学基金杰出青年基金 (ZRZ0273, 2013.1-2015.12)
9. 参与国家基础研究计划 (973项目: 2011CB808600, 2011.1-2015.8)
代表性成果
1. Liang Wei, Xin Chang, Chun-Jiang Wang* Catalytic Asymmetric Reactions with N-Metallated Azomethine Ylides. Acc. Chem. Res. 2020, 53, 1084-1100.
2. Shi-Min Xu, Liang Wei, Chong Shen, Lu Xiao, Hai-Yan Tao, Chun-Jiang Wang* Stereodivergent Assembly of Tetrahydro-γ-carbolines via sSnergistic Catalytic Asymmetric Cascade Reaction. Nat. Commun. 2019, 10, 5553.
3. Liang Wei, Qiao Zhu, Lu Xiao, Hai-Yan, Chun-Jiang Wang* Synergistic Catalysis for Cascade Allylation and 2-aza-Cope Rearrangement of Azomethine Ylides. Nat. Commun. 2019, 10, 1594.
4. Liang Wei, Qiao Zhu, Shi-Min Xu, Xin Chang, Chun-Jiang Wang* Stereodivergent Synthesis of α,α-Disustituted α-Amino Acids via Synergistic Cu/Ir Catalysis. J. Am. Chem. Soc. 2018, 140, 31508-1513.
5. Liang Wei,Shi-Min Xu, Qiao Zhu, Chao Che, Chun-Jiang Wang* Synergistic Cu/Pd Catalysis for Enantioselective Allylic Alkylation of Aldimine Esters: Access to a,a-Disustituted a-Amino Acids. Angew. Chem. Int. Ed. 2017, 56, 12312-12316.
6. Rong Huang, Xin Chang, Jun Li, Chun-Jiang Wang* Cu(I)-Catalyzed Asymmetric Multicomponent Cascade Inverse Electron-Demand Aza-Diels Alder/Nucleophilic Addition/Ring-Opening Reaction Involving 2-Methoxyfurans as Efficient Dienophiles. J. Am. Chem. Soc. 2016, 138, 3998-4001.
7. Lu Yao, Qiao Zhu, Liang Wei, Zuo-Fei Wang, Chun-Jiang Wang* Dysprosium(III)-Catalyzed Ring-Opening of meso-Epoxides: Remote Stereocontrol Desymmetrization via a Cascade Thiolysis/Elimination Sequence. Angew. Chem., Int. Ed. 2016, 55, 5829-5833.
8. Jun Li; Rong Huang, Yi-Kang Xing, Guofu Qiu,Hai-Yan Tao, Chun-Jiang Wang* Catalytic Asymmetric Cascade Vinglogous Mukaiyama 1,6-Michael/Michael Addition of 2-Silyloxyfurans with Azoalkenes: Direct Approach to Fused Butyrolactones. J. Am. Chem. Soc. 2015, 137, 10124-10127.
9. Qing-Hua Li; Liang Wei; Chun-Jiang Wang* Catalytic Asymmetric 1,3-Dipolar [3 + 6] Cycloaddition of Azomethine Ylides with 2-Acyl Cycloheptatrienes: Efficient Construction of Bridged Heterocycles Bearing Piperidine Moiety. J. Am. Chem. Soc. 2014, 136, 8685-8692.
10. Min-Chao Tong; Xuan Chen; Jun Li; Rong Huang; Haiyan Tao; Chun-Jiang Wang* Catalytic Asymmetric Synthesis of [2,3]-Fused Indoline Heterocycles through Inverse-Electron-Demand Aza-Diels–Alder Reaction of Indoles with Azoalkenes. Angew. Chem., Int. Ed. 2014, 53, 4680-4684.
11. Huai-Long Teng; Lu Yao; Chun-Jiang Wang* Cu(I)-Catalyzed Regio- and Stereoselective [6 + 3] Cycloaddition of Azomethine Ylides with Tropone: An Efficient Asymmetric Access to Bridged Azabicyclo[4.3.1]decadienes. J. Am. Chem. Soc. 2014, 136, 4075-4080.
12. Zhao-Lin He; Huai-Long Teng; Chun-Jiang Wang* Fulvenes as Effective Dipolarophiles in Copper(I)-Catalyzed [6 + 3] Cycloaddition of Azomethine Ylides: Asymmetric Construction of Piperidine Derivatives. Angew. Chem., Int. Ed. 2013, 52, 2934-2938.
13. Min-Chao Tong; Xuan Chen; Hai-Yan Tao; Chun-Jiang Wang* Catalytic Asymmetric 1,3-Dipolar Cycloaddition of Two Different Ylides: Facile Access to Chiral 1,2,4-Triazinane Frameworks. Angew. Chem., Int. Ed. 2013, 52, 12377-12380.
14. Zhi-Yong Xue; Qing-Hua Li; Hai-Yan Tao; Chun-Jiang Wang* A Facile Cu(I)/TF-BiphamPhos-Catalyzed Asymmetric Approach to Unnatural α-Amino Acid Derivatives Containing gem-Bisphosphonates. J. Am. Chem. Soc. 2011, 133, 11757-11765.
15. Chun-Jiang Wang;* Gang Liang; Zhi-Yong Xue; Feng Gao. Highly Enantioselective 1,3-Dipolar Cycloaddition of Azomethine Ylides Catalyzed by Copper(I)/TF-BiphamPhos Complexes. J. Am. Chem. Soc. 2008, 130, 17250-17251.
16. Chun-Jiang Wang;* Xiu-Qin Dong; Zhi-Hai Zhang; Zhi-Yong Xue; Huai-Long Teng. Highly anti-selective asymmetric nitro-Mannich reactions catalyzed by bifunctional amine-thiourea-bearing multiple hydrogen-bonding donors. J. Am. Chem. Soc. 2008, 130, 8606-8607.
17. Xin Fang, Chun-Jiang Wang* Recent Advances in Asymmetric Organocatalysis Mediated by Bifunctional Amine-Thioureas Bearing Multiple Hydrogen-Bonding Donors. Chem. Commun. 2015, 51, 1185-1197 (Invited Feature Article).
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